Threre seem to be issues in #Linux#Kernel 5.10.4+ - somehow related to audio via hdmi maybe, usually results in random gfx glitches and gpu hangs/system freezes. snd_hda_codec_hdmi errors or gpu hang messages (in log / dmesg) might confirm this. Rolling back to Kernel <= 5.10.3 or blacklisting snd_hda_codec_hdmi might help mitigating.
Disabling silent streams for snd_hda actually also seem to do the trick and keeps hdmi audio working: Inject the following to modprobe: options snd_hda_codec_hdmi enable_silent_stream=N