I disrecommend to set "Autosuspend for USB device …" to good if the USB device is a mouse or keyboard.
I just tested this and was very annoying to press a key on my keyboard and nothing happened. Same with the mouse. Pushing her around but nothing happened. Pressing a key 2 seconds later or moving the mouse for more than 2 seconds and everything works as expected but this does not help with the initial annoyance when nothing happens.
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